The history of Château Lilian Ladouys is inseparable from that of the Médoc. The existence of the 'La Doys' estate, a name which makes reference to the source in the Gascon language, can be traced back to 1564 when it was held in fief by Jacques de Becoyran, lord of Lafite. Château Lafite Rothschild is in fact just a few hundred metres away from the estate."

In 2008, Jacky and Françoise Lorenzetti acquired the estate after falling in love with it. They very quickly poured passion and ambition in the estate, launching a vast reparcelling programme. Construction work on a new semi-underground vat house was begun in 2009. The image of a four-leaf clover appearing on the walls of the chateau became the winegrowing emblem of Lilian Ladouys and features on the label.

By a quirk of fate, it can also be found on the rear wall of Château Pédesclaux, a Pauillac Grand Cru Classé under the 1855 classification which was acquired in 2009. Jacky and Françoise have also been co-owners of Château d'Issan, a Margaux Grand Cru Classé, since 2013.